Table 2. Comparison of clinicopathologic features among patients harboring different genes.
Variables | ALK | ROS1 | Wild type | P (ALK vs. wild) | P (ROS1 vs. wild) |
---|---|---|---|---|---|
Gender | 0.19 | 0.39 | |||
Male | 42 | 15 | 334 | ||
Female | 47 | 17 | 277 | ||
Age at diagnosis (years) | 0.08 | 0.65 | |||
<60 | 58 | 19 | 338 | ||
≥60 | 31 | 13 | 273 | ||
Smoking history | <0.001 | 0.0002 | |||
Yes | 19 | 5 | 299 | ||
No | 70 | 27 | 312 | ||
Histology | 0.006 | 0.015 | |||
Solid predominant | 18 | 8 | 66 | ||
Non-solid predominant | 56 | 20 | 460 | ||
Stage at diagnosis | 0.14 | 0.55 | |||
I–IIIA | 67 | 20 | 413 | ||
IIIB/IV | 22 | 12 | 198 | ||
TTF1 | 0.01 | 0.035 | |||
Positive | 70 | 26 | 413 | ||
Negative | 5 | 0 | 90 | ||
Napsin A | 0.04 | 0.25 | |||
Positive | 76 | 28 | 443 | ||
Negative | 2 | 0 | 52 | ||
P63 | 0.32 | 0.57 | |||
Positive | 1 | 0 | 24 | ||
Negative | 64 | 21 | 435 | ||
CK5/6 | 0.39 | 0.40 | |||
Positive | 2 | 0 | 29 | ||
Negative | 72 | 26 | 462 |