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. 2017 Nov 27;13(12):1520–1531. doi: 10.7150/ijbs.21107

Figure 1.

Figure 1

NBP inhibits BSCB disruption and improves locomotion recovery following SCI. NBP was administered by oral gavage after SCI and the permeability of BSCB was tested at 24 h after injury with Evan's Blue dye. (A) Typical spinal cords dispaly that Evan's Blue dye permeated into the injury spinal cord tissue at 24 h post-SCI. Compared to the SCI group, NBP treatment reduced the quantity of Evan's Blue dye in the surface of spinal cord (n=5 per group). (B) The BBB scores of the Sham, SCI and NBP treatment groups (n=8 per group). NBP improved functional recovery at 7 day after injury. * P < 0.05 versus the SCI group. (C) Quantify of the quantity of Evan's Blue dye of the Sham, SCI and NBP treatment groups at 24 h post-SCI (n=5 per group). # P<0.05 versus the SCI group, * P<0.01 versus the Sham group. (D) Typical confocal pictures of Evan's Blue leakage in each group (n=5 per group).