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. 2017 Sep 25;292(49):20032–20043. doi: 10.1074/jbc.M117.801225

Table 1.

Summary of all model evaluations

The threshold for the χ2 error for 95% significance is calculated using the number of data points (28 in the original data and 39 in the extended data) minus 1 normalization parameter minus the number of parameters in the model.

Agreement with original data (χ2 error; threshold) Conclusion from original data agreement Agreement with extended data (original data + >10 μm free Ca2+ + 0 cAMP) (χ2 error; threshold) Final conclusion
Exocytosis model, original (11 parameters) 62 (>26) Rejected Rejercted
Exocytosis model, ATP (12 parameters) 31 (>25) Rejected Rejected
Exocytosis model, ATP/endocytosis (15 parameters) 11 (<21) Not rejected 20 (<35) Agreement with all data