Figure 1.

Fig. 1 FplA is a Type Vd autotransporter phospholipase from F. nucleatum. A, schematic representation of FplA domains and their location in the periplasm, outer membrane, and surface exposure of the PLA₁ domain. Experimental data show FplA to be cleaved in a select set of F. nucleatum species, but the phospholipase domain remains associated with the bacterium. B, structure prediction of FplA domains: modeled patatin domain (residues 60–341) from PDB entry 5FYA (PlpD from P. aeruginosa); modeled β barrel (residues 432–759) and POTRA domain (residues 359–431) from PDB entry 4K3C (BamA from H. ducreyi).