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Psychophysiological interaction results when seeding from the middle frontal gyrus. The figure shows the AS x PHYS > Scrambled Control x PHYS contrast for (A) high-risk and (B) low-risk subjects. Results are cluster corrected for multiple comparisons with the cluster defining threshold set at Z = 2.3 and a cluster extent threshold of P <0.05. Note: No activations survived thresholding for high-risk subjects. The red circle represents the seed ROI.
