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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Mol Microbiol. 2017 Jul 21;105(5):810–824. doi: 10.1111/mmi.13738

Figure 6. dig1Δ/dig1Δ is defective in colonization of the murine GI tract.

Figure 6

Mice were inoculated by oral gavage with wild type (JDM001, leu2−ura3−) or dig1Δ/dig1Δ (HJR6, leu2−ura3−) C. albicans strains and sacrificed after 1, 3 or 6 days before harvesting, extraction and quantification of genomic fungal DNA content. Each symbol represents cecal fungal burden for individual mice. Black bars indicate the geometric mean for samples that were positive for the C. albicans genomes. Open symbols indicate samples that were below the limit of detection. The Y-axis shows Genome equivalents per gram (measured in arbitrary units) as detected by real time PCR normalized to the wet weight of pelleted cecum contents. The X-axis shows Day post-inoculation. WT (red) and mutant (blue) samples were collected on the same day and are offset for clarity.