Table 1.

Primary outcomes

Primary outcomes	Variable/instrument	T1	T2	T3	T4
Empathy	Interpersonal Reactivity Index31	X	X	X	X
Caregiver burden	Caregiver Reaction Assessment–Dutch33	X	X	X	X
Depressive complaints	Hospital Anxiety and Depression Scale–subscale depression35	X	X	X	X
Anxiety complaints	Hospital Anxiety and Depression Scale–subscale anxiety35	X	X	X	X
Quality of the relationship	Relationship Quality Index37	X	X	X	X
	Quality of the Relationship38	X	X	X	X
Caregiver’s sense of competence	Short Sense of Competence Questionnaire39	X	X	X	X

Note. T1: 1 week before the simulator training; T2: 1 week after the training; T3: 2.5 months after the training, T4: 12 months after T3.