Table III. Asc1p-neighbors during exponential growth. The ratios were normalized against the respective proteome value (if available). A two-sample t-test (or one-sample t-test if no proteome value was available) with a p value of 0.05 indicated the enrichment as statistically significant. Standard deviations and the number of identified biotinylation sites are listed. Exceptions of the described thresholds are indicated as follows: ^2/6 only two valid values available from six replicates; ^T elevated p value in the t-test; ^o one clear outlier was not considered for the calculation of mean and standard deviation. * Although the threshold for the wt-Asc1p control was not reached, Rpg1p was further considered as Asc1p-neighbor, because it is a subunit of eIF3, which is known to interact with Asc1p (21).