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. 2017 Nov 27;114(49):13000–13005. doi: 10.1073/pnas.1713462114

Fig. 5.

Fig. 5.

SNX8 is essential for host defense against L. monocytogenes infection in mice. (A) Effects of SNX8 deficiency on serum levels of CXCL9, CXCL10, and TNFα induced by i.p. injection of mice (n = 11 per group) with L. monocytogenes (4 × 106 each mouse) for 6 h (**P < 0.01). (B) Effects of SNX8 deficiency on bacterial loads in mice. Plaque assays of homogenized spleens and livers from mice (n = 6 per group) 3 d after i.p. injection of L. monocytogenes (4 × 106 each mouse) (**P < 0.01). (C) Survival of mice (n = 10 per group) after i.p. injection of L. monocytogenes (5 × 107 each mouse) (**P < 0.01).