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. 2017 Dec 11;12:27. doi: 10.1186/s13015-017-0118-8

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Empirical length distribution of k-mismatch common substring extensions. The number of k-mismatch extensions of length m was calculated with kmacs for a pair of simulated DNA sequences of length $L = 500$ kb with $k = 90$ and $80 \leq m \leq 240$ . The plot shows the raw frequencies and smoothed distribution with different values for for the width w of the smoothing window. The hight of the ‘homologous’ peak is > 50,000