Table 1.
Model | |||||||
BCF | LOCF | CA | ORC | RRC | Joint | ||
Survival model | |||||||
logHR | SBP | 0.019 (0.001) | 0.019 (0.001) | 0.022 (0.001) | 0.028 (0.002) | 0.027 (0.002) | 0.030 (0.002) |
SBP slope | NA | NA | NA | 0.076 (0.040) | 0.139 (0.041) | 0.155 (0.048) | |
3‐year CVD risk prediction | |||||||
C‐index | 0.750 (0.021) | 0.742 (0.022) | 0.751 (0.022) | 0.752 (0.022) | 0.750 (0.022) | 0.751 (0.022) | |
Change in C‐index | Reference | − 0.009 (0.009) | 0.000 (0.006) | 0.002 (0.006) | 0.000 (0.007) | 0.001 (0.007) | |
Brier score | 0.026 (0.002) | 0.026 (0.002) | 0.026 (0.002) | 0.026 (0.002) | 0.026 (0.002) | 0.026 (0.002) | |
10‐year CVD risk prediction | |||||||
C‐index | 0.728 (0.012) | 0.723 (0.012) | 0.732 (0.012) | 0.733 (0.012) | 0.732 (0.012) | 0.733 (0.012) | |
Change in C‐index | Reference | − 0.005 (0.005) | 0.004 (0.003) | 0.006 (0.003) | 0.004 (0.004) | 0.005 (0.004) | |
Brier score | 0.100 (0.004) | 0.100 (0.004) | 0.099 (0.004) | 0.099 (0.004) | 0.099 (0.004) | 0.099 (0.004) |
Changes in C‐indices are compared with the BCF model. SBP, systolic blood pressure; RRC, risk‐set regression calibration; BCF, baseline carried forward; LOCF, last observation carried forward; CA, cumulative average; ORC, ordinary regression calibration; CVD, cardiovascular disease.