Table 2. Impact of Pressure on k_cat-H at the Extremes of the Experimental Temperature Range^a.

entry	enzyme	T (K)	S344 bar	S688 bar	S1034 bar
1	WTb	288	1.00 (0.05)	0.97 (0.08)	0.97 (0.09)
2		308	1.40 (0.18)	1.50 (0.10)	1.77 (0.08)
3	I553 Vb	288	1.08 (0.09)	1.10 (0.13)	1.01 (0.19)
4		308	1.10 (0.02)	1.43 (0.03)	1.66 (0.03)
5	L546Ab	288	1.03 (0.02)	1.20 (0.06)	1.28 (0.03)
6		308	1.07 (0.02)	1.42 (0.07)	1.68 (0.07)
7	L754Ab	288	1.58 (0.10)	2.92 (0.14)	4.24 (0.24)
8		308	1.90 (0.13)	3.35 (0.20)	5.26 (0.44)
9	L546A/L754A	288	1.35 (0.12)	1.78 (0.15)	1.92 (0.14)
10		308	1.28 (0.07)	1.67 (0.15)	1.92 (0.14)

^aS is the ratio of k_cat-H at the pressure listed relative to ambient pressure (ref (31) and Table S2).

^bData from ref (31).