Table 5.
Independent Variables Associated with Clinician Intention to Prescribe Pre-Exposure Prophylaxis to Adolescents Younger than 18: Results of Unadjusted and Adjusted Logistic Regression Models
| Risk category | Variablea | Unadjusted OR (95% CI)b | Adjusted OR (95% CI)c |
|---|---|---|---|
| MSM | Greater endorsement of facilitating factors for prescribing PrEP | 2.73 (1.05–7.10) | 2.73 (1.05–7.10) |
| Lower percentage of patients younger than 18 in overall practice | 1.02 (1.00–1.04) | ||
| Fewer provider-level barriers to prescribing PrEP | 2.27 (0.86–5.88) | ||
| Fewer barriers related to PrEP use in patients younger than 18 | 2.13 (0.96–4.55) | ||
| Greater endorsement of facilitating factors for use of CDC guidance | 2.37 (0.88–6.42) | ||
| Transgender woman | Fewer provider-level barriers to prescribing PrEP | 3.33 (1.18–9.09) | 3.33 (1.18–9.09) |
| Lower endorsement of cost and insurance factors impacting clinician likelihood of prescribing PrEP | 1.92 (1.08–3.57) | ||
| Heterosexual with multiple partners | Belief that a multi-disciplinary team is not necessary to deliver PrEP | 4.67 (1.03–21.07) | 4.67 (1.03–21.07) |
| Heterosexual with HIV-infected partner | Nurse practitioner (vs. physician) | 4.80 (0.94–24.61) | 9.76 (1.3–73.59) |
| Lower endorsement of cost and insurance factors impacting clinician likelihood of prescribing PrEP | 2.08 (1.04–4.17) | 4.55 (1.59–14.29) | |
| Greater endorsement of facilitating factors for prescription of PrEP | 2.79 (0.99–7.90) | 7.40 (1.74–31.58) | |
| Fewer barriers related to PrEP use in patients younger than 18 | 2.94 (1.06–8.33) | ||
| Summary measure of all risk categories | More barriers related to cost and resource issues | 2.63 (1.03–6.71) | 5.92 (1.70–20.64) |
| Fewer provider-level barriers to prescribing PrEP | 2.94 (1.08–8.33) | 7.14 (1.85–33.33) |
a
Variables in bold are significant in the adjusted model (p < 0.05).
b
ORs presented are significant at p < 0.10 and were entered into the adjusted logistic regression model. ORs and CIs in bold are significant at p < 0.05.
c
ORs in bold were significant in the adjusted model (p < 0.05). Nonsignificant variables were not included in the final model.
CDC, Centers for Disease Control and Prevention; CI, confidence interval; MSM, men who have sex with men; OR, odds ratio; PrEP, pre-exposure prophylaxis.