Table 6.
Independent Variables Associated with Clinician Intention to Prescribe Pre-Exposure Prophylaxis to Adult Patients Age 18 and Older: Results of Unadjusted and Adjusted Logistic Regression Models
| Risk category | Variablea | Unadjusted OR (95% CI)b | Adjusted OR (95% CI)c |
|---|---|---|---|
| MSM | Lower knowledge about CDC PrEP guidance | 1.61 (0.93–2.78) | |
| Transgender woman | Lower knowledge about CDC PrEP guidance | 1.67 (0.94–2.94) | |
| Heterosexual with multiple partners | Nurse practitioner (vs. physician) | 5.83 (1.56–21.87) | 7.22 (1.68–30.93) |
| Older age for lower limit of age of patients in practice | 0.92 (0.84–1.00) | 0.90 (0.81–0.99) | |
| Lower knowledge about CDC PrEP guidance | 1.69 (1.01–2.86) | ||
| More barriers related to cost and resource issues | 2.19 (0.90–5.32) | ||
| Heterosexual with HIV-infected partner | Nurse practitioner (vs. physician) | 7.73 (0.90–66.39) | 11.61 (1.16–115.81) |
| Fewer barriers related to PrEP use in adolescents younger than 18 | 3.03 (0.96–9.09) | 4.55 (1.08–20.00) | |
| Lower endorsement of cost and insurance factors impacting clinician likelihood of prescribing PrEP | 1.92 (0.93–4.00) | ||
| Summary measure of all risk categories | Lower knowledge about CDC PrEP guidance | 1.82 (1.08–3.13) | 1.82 (1.08–3.13) |
| Greater endorsement of cost and resource issues impacting prescription of PrEP | 2.55 (1.01–6.43) | ||
| Nurse practitioner (vs. physician) | 3.33 (0.99–11.22) | ||
| Older age for lower limit of age of patients in practice | 0.93 (0.85–1.01) |
a
Variables in bold are significant in the adjusted model (p < 0.05).
b
ORs presented are significant at p < 0.10 and were entered into the adjusted logistic regression model. ORs and CIs in bold are significant at p < 0.05.
c
ORs in bold were significant in the adjusted model (p < 0.05). Nonsignificant variables were not included in the final model.
CDC, Centers for Disease Control and Prevention; CI, confidence interval; MSM, men who have sex with men; OR, odds ratio; PrEP, pre-exposure prophylaxis.