Table 7.
Independent Variables Associated with Actual Clinician Prescription of Pre-Exposure Prophylaxis Overall: Results of Unadjusted and Adjusted Logistic Regression Models
| Variablea | Unadjusted OR (95% CI)b | Adjusted OR (95% CI)c |
|---|---|---|
| Urban practice location (vs. suburban) | 1.99 (1.31–3.01) | |
| Prescribed nPEP ≥2 times to adults age 18 and older (vs. 0–1 time) | 5.26 (1.64–16.67) | |
| Prescribed nPEP ≥2 times to patients younger than 18 (vs. 0–1 time) | 2.22 (0.98–5.00) | |
| Discussed PrEP with HIV-infected patients ≥2 times (vs. 0–1 time) | 20.00 (3.22–100.00) | 12.5 (1.96–100.00) |
| Discussed PrEP with HIV-uninfected patients ≥2 times (vs. 0–1 time) | 10.00 (3.70–25.00) | 7.14 (2.94–20.00) |
| Belief that behavioral interventions are not necessary for PrEP delivery | 2.99 (0.84–10.70) | |
| Greater number of HIV-infected patients younger than 18 cared for by clinician per week | 1.03 (1.00–1.07) | |
| Older upper age of patients in overall practice | 1.02 (1.00–1.03) | |
| Fewer provider-level barriers to prescribing PrEP | 2.27 (1.19–4.17) | 2.08 (1.01–4.35) |
| Patient age ≥18 years (vs. <18 years) | 2.09 (1.38–3.15) | 2.60 (1.51–4.48) |
| Risk group (vs. heterosexual with multiple partners) | ||
| Heterosexual with HIV-infected partner | 2.12 (1.05–4.27) | 2.38 (1.07–5.28) |
| MSM | 5.82 (2.93–11.60) | 8.49 (3.68–19.60) |
| Transgender woman (vs. heterosexual with multiple partners) | 1.41 (0.55–3.64) | 1.48 (0.51–4.30) |
Variables in bold are significant in the adjusted model (p < 0.05).
ORs presented are significant at p < 0.10 and were entered into the adjusted logistic regression model. ORs and CIs in bold are significant at p < 0.05.
ORs in bold were significant in the adjusted model (p < 0.05). Nonsignificant variables were not included in the final model except as part of a grouped analysis (i.e., transgender woman vs. heterosexual with multiple partners).
CDC, Centers for Disease Control and Prevention; CI, confidence interval; MSM, men who have sex with men; nPEP, nonoccupational postexposure prophylaxis; OR, odds ratio; PrEP, pre-exposure prophylaxis.