Table 9.
Independent Variables Associated with Actual Clinician Prescription of Pre-Exposure Prophylaxis to Adolescents Younger than 18: Results of Unadjusted and Adjusted Logistic Regression Models
| Risk category | Variablea | Unadjusted OR (95% CI)b | Adjusted OR (95% CI)c |
|---|---|---|---|
| MSM | Ever prescribed nPEP to an adolescent younger than 18 (vs. never prescribed) | 7.14 (1.85–25.00) | 12.50 (2.27–50.00) |
| Belief that behavioral interventions are not necessary for PrEP delivery | 6.18 (0.99–38.48) | 14.83 (1.56–141.48) | |
| Fewer provider-level barriers to prescribing PrEP | 3.33 (1.14–10.00) | ||
| Prescribed nPEP ≥2 times to adults age 18 and older (vs. 0–1 time) | 9.09 (1.79–50.00) | ||
| Lower endorsement of cost and insurance factors impacting clinician likelihood of prescribing PrEP | 1.75 (0.95–3.33) | ||
| Fewer barriers related to PrEP use in patients under age 18 | 2.00 (0.92–4.35) | ||
| Transgender woman | Years since graduation from professional school | 1.09 (1.00–1.18) | 1.24 (1.02–1.51) |
| Fewer provider-level barriers to prescribing PrEP | 7.14 (1.09–50.00) | 50.00 (1.54–1000) | |
| Fewer barriers related to PrEP use in patients younger than 18 | 3.23 (1.00–10.00) | ||
| Heterosexual with multiple partners | Greater number of patients younger than 18 cared for by clinician per week | 1.04 (0.99–1.10) | |
| Greater number of HIV-infected patients younger than 18 cared for by clinician per week | 1.06 (1.00–1.13) | ||
| Belief that behavioral interventions are not necessary for PrEP delivery | 6.83 (0.87–53.77) | ||
| Heterosexual with HIV-infected partner | Greater number of HIV-infected patients younger than 18 cared for by clinician per week | 1.07 (1.01–1.14) | 1.07 (1.01–1.14) |
| Greater knowledge about PrEP | 2.11 (0.88–5.06) | ||
| Summary measure of all risk categories | Prescribed nPEP ≥2 times to adults age 18 and older (vs. 0–1 time) | 14.29 (1.54–100.00) | 14.29 (1.54–100.00) |
| Fewer provider-level barriers to prescribing PrEP | 4.17 (1.16–14.29) | ||
| Fewer barriers related to PrEP use in patients younger than 18 | 2.13 (0.90–5.00) |
a
Variables in bold are significant in the adjusted model (p < 0.05).
b
ORs presented are significant at p < 0.10 and were entered into the adjusted logistic regression model. ORs and CIs in bold are significant at p < 0.05.
c
ORs in bold were significant in the adjusted model (p < 0.05). Nonsignificant variables were not included in the final model.
CI, confidence interval; MSM, men who have sex with men; nPEP, nonoccupational postexposure prophylaxis; OR, odds ratio; PrEP, pre-exposure prophylaxis.