Fig. 2.

Axial T2W image (a), monoexponential apparent diffusion coefficient map (b, calculated using b-values in the range of 0–500 s/mm²), sagittal T2W image (c), trace diffusion-weighted image of b-value 1500 s/mm² (d), and trace diffusion-weighted image of b-value 2000 s/mm² (e) acquired using a 1.5-T MR scanner with an acquisition time < 13 min (IMPROD_Siemens_1_5T.pdf/.edx). The suspicious lesion in the apex (write arrows) was interpreted as Likert score 5, PI-RADsv2 4, and DWI score 1 (dominant Gleason grade 4 is probable). Prostate cancer with Gleason score 4 + 3 was found in two cores of the targeted biopsy while no cancer was present in the cores the systematic biopsy. Clinically significant prostate cancer was found only in the targeted biopsy cores, and the prediction of the Gleason score based on DWI was correct. The MR acquisition protocol (IMPROD_Siemens_3T.pdf, IMPROD_Siemens_3T.edx) and reporting system (IMPROD_trial_instructions.pdf) are provided in the supporting material.