Table 5.
Costs of adverse events and skeletal-related events
| Events | Management cost per episode, € | Source | Notes |
|---|---|---|---|
| Anemia | 1,238.76 | Restelli et al47 | Epoetin alfa + blood transfusion (blood transfusion in 10% of patients) |
| Thrombocytopenia | 20.69 | Restelli et al47 | Specialist visit |
| Neutropenia | 413.02 | Restelli et al47 | Antibiotics + granulocyte – colony-stimulating factor |
| Febrile neutropenia | 782.34 | Restelli et al47 | Granulocyte – colony stimulating factor + hospitalization in 10% of patients (DRG 574) |
| Diarrhea | 20.69 | Restelli et al47 | Specialist visit |
| Nausea | 226.23 | Restelli et al47 | Antiemetic therapy |
| Vomiting | 226.23 | Restelli et al47 | Antiemetic therapy |
| Fatigue | 1,236.18 | Restelli et al47 | Epoetin alfa |
| Non-vertebral fracture | 2,295 | Hechmati et al41 | – |
| Vertebral fracture | 2,356 | Hechmati et al41 | – |
| Radiation to bone | 2,706 | Hechmati et al41 | – |
| Spinal cord compression | 5,371 | Hechmati et al41 | – |
| Surgery to bone | 3,682 | Hechmati et al41 | – |
Abbreviation: DRGs, diagnosis related groups.