Table 1.
Vitamin E levels in Xpg−/− mice at 8 and 12 weeks
Micronutrient (time point) | Diet | Plasma ± s.e.m. (nmol/L) | Liver ± s.e.m. (nmol/g) | Brain ± s.e.m. (nmol/g) |
---|---|---|---|---|
α-Tocopherol (8 weeks) | Low | 1878 ± 93 a=*** | 63 ± 14 a=* | 107 ± 12 a=** |
Medium | 20214 ± 1214 b=** | 1772 ± 418 b=ns | 276 ± 9 b=ns | |
High | 26478 ± 1140 c=*** | 5282 ± 1455 c=* | 344 ± 53 c=* | |
α-Tocopherol (12 weeks) | Low | 1767 ± 100 a=*** | 46 ± 12 a=** | 114 ± 9 a=** |
Medium | 17829 ± 901 b=*** | 931 ± 172 b=* | 348 ± 39 b=ns | |
High | 25773 ± 972 c=*** | 3808 ± 423 c=** | 643 ± 111 c=* |
Amount of α-Tocopherol in the plasma (nmol/L, n=7), liver and brain (nmol/g, n=2 for all and n= 3 for high vitamin E diet at 12 weeks) of 8 and 12 weeks old Xpg−/− mice. Errors represent s.e.m. values. a = compares low with medium vitamin E group; b = medium vs high; c = high vs low; ns: not significant.