Table 4. Toxicity and global QOL association.

The global quality of life (QOL) score at each time point was analyzed for its association with a patient’s treatment-related toxicities. The presence or absence of grade 3 or greater toxicities, the number of toxicities across all systems, or the cumulative grades of all toxicities were analyzed. The cumulative grades of toxicities represent the sum of the toxicity grades from every system.

	Association with global QOL score (Spearman’s Correlation Coefficient)	p-value
Presence or absence of grade 3+ toxicities	-0.138	0.236
Number of toxicities across all systems	-0.373	0.001
Cumulative grades of all toxicities	-0.495	<0.001