Table 5. Lipid parameters expressed in mM in all study participants between baseline and 12 weeks in the active (Lactobacillus plantarum ECGC 13110402) and placebo treatment groups.
| Outcome | Group | N | Baseline Mean (SD) |
12 weeks Mean (SD) |
Change Mean (SD) [range] |
% Change Mean (SD) [range] |
Group Difference Mean (95% CI) | P-value |
|---|---|---|---|---|---|---|---|---|
| TC | Placebo | 23 | 5.22 (0.92) | 5.33 (0.84) | 0.11 (0.66) [-1.0, 1.4] | 3.1 (13.4) [-14.6, 34.1] | 0 | |
| Active | 23 | 5.10 (0.71) | 5.12 (0.87) | 0.02 (0.56) [-1.3, 1.2] | 0.6 (10.5) [-22.4, 23.3] | -0.12 (-0.47, 0.24) | 0.51 | |
| HDL-C | Placebo | 23 | 1.24 (0.31) | 1.24 (0.29) | 0.00 (0.17) [-0.2, 0.5] | 1.5 (17.0) [-14.3, 62.5] | 0 | |
| Active | 23 | 1.40 (0.35) | 1.46 (0.42) | 0.06 (0.15) [-0.1, 0.5] | 3.4 (10.5) [-12.5, 33.3] | 0.06 (-0.04, 0.16) | 0.023 | |
| LDL-C | Placebo | 23 | 3.44 (0.76) | 3.54 (0.70) | 0.10 (0.62) [-0.9, 1.3] | 4.9 (19.5) [-22.9, 52.0] | 0 | |
| Active | 23 | 3.20 (0.69) | 3.13 (0.78) | -0.07 (0.53) [-1.3, 1.0] | -1.4 (15.6) [-36.4, 26.3] | -0.24 (-0.56, 0.09) | 0.15 | |
| TAG | Placebo | 23 | 1.18 (0.45) | 1.20 (0.39) | 0.03 (0.41) [-0.9, 0.6] | 10.9 (35.7) [-52.9. 83.3] | 0 | |
| Active | 23 | 1.11 (0.46) | 1.15 (0.65) | 0.04 (0.36) [-0.5, 0.8] | 3.6 (34.8) [-55.6, 114.3] | 0.01 (-0.22, 0.23) | 0.96 |
TC: total cholesterol; HDL-C: High-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TAG: triacylglycerol; N: number of participants