Fig 2. Manhattan plot for genome-wide association analyses of rotator cuff injury.

The log₁₀ p-values for association with rotator cuff injury for 10,582,947 SNPs from the meta-analysis from this study are plotted by genomic position with chromosome number listed across the bottom. The y-axis shows the -log₁₀ p-value for association with rotator cuff injury. The blue line represents suggestive genome-wide significance (p<1x10^-5) and the red line represents genome-wide significance (p<5x10^-8). The top SNP rs71404070 and the nine other SNPs within the same linkage disequilibrium block at suggestive significance are highlighted in green.