Table 3. The frequencies of haplotypes of RAGE and HMGB1 gene in patients and controls.

Haplotypes	Case (n%)	Control (n%)	OR (95%)	P value	P value *
RAGE (rs184003, rs1035798, rs2070600, rs1800624, rs1800625)
G-G-C-T-T	879.0 (42.5)	858.0 (42.3)	1.00
G-G-T-T-T	432.0 (20.9)	370.0 (18.2)	1.14(0.96-1.35)	0.13	0.47
T-G-C-T-T	344.0 (16.7)	372.0 (18.3)	0.90 (0.76-1.07)	0.25	0.47
G-A-C-A-T	243.0 (11.8)	259.0 (12.8)	0.92 (0.75-1.12)	0.39	0.47
G-G-C-T-C	151.0 (7.3)	161.0 (7.9)	0.92 (0.72-1.17)	0.47	0.47
HMGB1 (rs1045411, rs3742305, rs2249825)
G-G-C	1618 (78.6)	1539 (76.1)	1.00
A-C-G	305 (14.8)	352 (17.4)	0.83 (0.70-0.98)	0.024	0.048
A-C-C	129 (6.3)	128 (6.3)	0.96 (0.74-1.24)	0.75	0.75

Adjusted for age, gender, smoking, hypertension, diabetes mellitus, and hyperlipidaemia.

^*False discovery rate-adjusted P value for multiple hypotheses testing using the Benjamini-Hochberg method.