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. 2017 Oct 27;8(59):100216–100226. doi: 10.18632/oncotarget.22145

Figure 5. Apigenin suppresses the NF-κB/STAT3 pathway in colon carcinoma cells.

Figure 5

(A) Dual-luciferase assay results for NF-κB transcription in HCT-116 cells. (B) Levels of p-NF-κB p65 and T-NF-κB p65 after LPS administration in HCT-116 cells treated with apigenin or vehicle. (C) Dual-luciferase assay results for STAT3 in HCT-116 cells. (D) Levels of p-STAT3 and T-STAT3 after LPS administration in HCT-116 cells treated with apigenin or vehicle. (E) Levels of secreted IL-6 and IL-10 after LPS administration in HCT-116 cells treated with apigenin or vehicle. (F) Expression of p-STAT3 and T-STAT3 in HCT-116 cells pretreated with HO-3867.