Table 4. Genotype frequencies of CYP1A2, FMO1, FMO3, NR1I2, SULT1E1, andUGT2B15 genes.
| Polymorphism | Genotype, n (%) | ||
|---|---|---|---|
| Wild homozygote | Heterozygote | Variant homozygote | |
| CYP1A2 -3860G>A | 46 (57.5) | 30 (37.5) | 4 (5.0) |
| CYP1A2 -2467delT | 21 (26.3) | 42 (52.5) | 17 (21.3) |
| CYP1A2 -739T>G | 70 (87.5) | 10 (12.5) | 0 (0.0) |
| CYP1A2 -163A>C | 32 (41.6) | 40 (51.9) | 5 (6.5) |
| CYP1A2 5347C>T | 52 (65.0) | 26 (32.5) | 2 (2.5) |
| FMO1 747C>T | 78 (97.5) | 2 (2.5) | 0 (0.0) |
| FMO1 1188A>G | 78 (97.5) | 2 (2.5) | 0 (0.0) |
| FMO1 *111C>T | 43 (54.4) | 31 (39.2) | 5 (6.3) |
| FMO1 *207C>T | 41 (51.3) | 34 (42.5) | 5 (6.3) |
| FMO3 441C>T | 48 (60.0) | 30 (37.5) | 2 (2.5) |
| FMO3 472G>A | 55 (68.8) | 22 (27.5) | 3 (3.8) |
| FMO3 627+10C>G | 78 (97.5) | 2 (2.5) | 0 (0.0) |
| FMO3 769G>A | 58 (75.3) | 15 (19.5) | 4 (5.2) |
| FMO3 923A>G | 56 (70.9) | 19 (24.1) | 4 (5.1) |
| NR1I2 -1135C>T | 41 (52.6) | 31 (39.7) | 6 (7.7) |
| SULT1E1 -64G>A | 40 (50.0) | 32 (40.0) | 8 (10.0) |
| SULT1E1 -9-899G>A | 48 (60.0) | 27 (33.8) | 5 (6.3) |
| SULT1E1 -9-682A>G | 67 (84.8) | 12 (15.2) | 0 (0.0) |
| SULT1E1 -9-469A>G | 34 (42.5) | 35 (43.8) | 11 (13.8) |
| SULT1E1 -10+311G>C | 34 (42.5) | 35 (43.8) | 11 (13.8) |
| UGT2B15 253G>T | 18 (22.5) | 46 (57.5) | 16 (20.0) |
| UGT2B15 1568A>C | 63 (78.8) | 14 (17.5) | 3 (3.8) |
| UGT2B15 *185A>T | 46 (57.5) | 29 (36.3) | 5 (6.3) |
Genotype frequencies of variants with minor allele frequency ≥ 1% and call rate > 85% are listed.