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. 2017 Nov 1;8(59):100326–100338. doi: 10.18632/oncotarget.22222

Figure 4. A combination therapy of alisertib plus VCR plus pan-PI3K inhibition induces apoptotic cell death.

Figure 4

CRL 2396 cells (A) were treated with 50nM alisertib, 1.5μM PF04691502, 0.75nM vincristine and their combination for 4 days and SUP-T1 cells (C) were treated with 50nM alisertib, 500nM PF04691502, 2.0nM vincristine and their combination for 4 days followed by Flow cytometry for analysis of apoptosis; quantified and expressed as mean ± S.E. in (B) and (D) respectively.