Table 1. Main characteristics of studies included in the meta-analysis.
| Study | Country | Number of patients | Sex | Median age | TNM stage | Deep of invasion | LN metastasis | Vascular invasion | Lymphatic invasion | Histological type | Size | Detection method | HMGA2-positive ratio(%) | Survival data type | Quanlity score |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMGA2+vs HMGA2- |
Male/ female |
I+II/III+IV | T1+T2/ T3+T4 |
Present/ absent |
Present/ absent |
Present/ absent |
Well+moderately/ poorly | >3cm/ <=3cm |
|||||||
| Dequan et al. (2014) | China | 158 68vs90 |
104/54 | NR | 57/101 | 86/72 | 93/65 | 61/97 | NR | 117/41 | 63/95 | IHC | 43.0 | OS | 7 |
| Junhy et al. (2015) | Korea | 170 39vs131 |
123/47 | 61.5(29-89) | 75/96 | 35/135 | 105/65 | 19/151 | 136/34 | 51/119 | NR | IHC | 22.9 | OS | 7 |
| Kazuo et al. (2008) | Japan | 110 55vs55 |
72/38 | NR | 59/51 | 67/43 | 78/32 | 30/80 | 78/32 | 55/55 | 87/23 | IHC | 50.0 | OS | 7 |
| Kyong-Hwa et al. (2015) | Korea | 110 72vs38 |
67/43 | 63.7(NR) | 59/51 | 33/77 | 73/37 | 22/88 | 68/42 | 57/53 | NR | IHC | 65.5 | DFS | 7 |
| LV Bonan et al. (2014) | China | 93 68vs25 |
56/37 | 54(39-76) | 26/67 | 33/60 | 55/38 | NR | NR | NR | NR | IHC | 73.1 | OS | 8 |
| ZHA Lang et al. (2011) | China | 71 46vs27 |
45/26 | 53(29-81) | 25/46 | NR | 49/22 | NR | NR | 29/42 | 48/32 | IHC | 64.8 | NR | 6 |
Abbreviations: DFS=disease free survival, IHC = immunohistochemistry, LN= Lymph node, NA= not available, OS=overall survival.