Figure 8. The blockage effect of PFTα against alcohol-induced anti-osteogenesis rat femoral head.

The fluorochrome labeling analysis showed significantly decreased bone formation in the femoral heads and the process of self-repair. (A) Tetracycline (yellow, 2 weeks), alizarin red (red, 4 weeks) and calcein (green, 6weeks) were all found to be deposited onto a broader area of subchondral femoral head trabecular bone in the NC group. (B) Fewer subchondral areas of the femoral head were stained with tetracycline, alizarin red and calcein, suggesting decreased new bone formation in the femoral head. (C) PFTα injection reversed the inhibitory effect of ethanol on new bone formation in rat femoral heads. Tetracycline, alizarin red and calcein were deposited onto larger areas of subchondral trabecular bone than what was observed in the AL group.