Table 3. Adverse events.

Adverse events (%)	All grades n (%)	Grade ≥ 3 n (%)
Fatigue	12 (63.15)	0 (0)
Headache/Dizzy	3 (15.79)	0 (0)
Diarrhea	11 (57.89)	1 (5.26)
Anorexia	9 (47.37)	0 (0)
Vomit	0 (0)	0 (0)
Stomachache	0 (0)	0 (0)
Nausea	4 (21.05)	0 (0)
Alimentary tract hemorrhage	0 (0)	0 (0)
Dysphagia	0 (0)	0 (0)
Pharyngolaryngeal pain	1 (5.26)	0 (0)
Dyspepsia	6 (31.58)	0 (0)
Mucositis oral	3 (15.79)	0 (0)
Dysgensia	0 (0)	0 (0)
HFSR	17 (89.47)	1 (5.26)
Hypertension	15 (78.95)	0 (0)
Proteinuria	6 (31.58)	0 (0)
Elevated transaminase	1 (5.26)	0 (0)
Hyperbilirubinemia	1 (5.26)	0 (0)
Elevated GGT	0 (0)	0 (0)
Alkaline phosphatase	0 (0)	0 (0)
Hypoproteinemia	2 (10.53)	0 (0)
Leukopenia	0 (0)	0 (0)
Neutropenia	0 (0)	0 (0)
Aglobulism	0 (0)	0 (0)
Thrombocytopenia	5 (26.32)	0 (0)
Hoarseness	1 (5.26)	0 (0)

HFSR: hand-foot-skin reaction; GGT: gamma-glutamyl transpeptidase.