Table 1. Classification of urate transporters.

Classification of urate transporters			The main distribution
Urate reabsorption transporter	Urate anion transporter 1(URAT1)		Located in the lumen side of the proximal tubular epithelial cells membrane
	Urate anion transporter 1(URAT1)		Expressed in both lumen and basolateral side of the proximal tubular epithelial cells membrane
Urate excretion transporter	Tubular cell uptake of uric acid transporters	Organic anion transporter 1(OAT1)	Expressed inbasolateral side of the proximal tubular epithelial cells membrane
		Organic anion transporter 3(OAT3)	Expressed inbasolateral side of the proximal tubular epithelial cells membrane
	Tubular cell secretion of uric acid transporters	Urate transporter	Expressed inbasolateral side of the proximal tubular epithelial cells membrane
		Multidrug resistance protein 4(MRP4)	Located in the tubular epithrlial cells brush border
		ABCG-2	Located in both apical and basolateral side of the proximal tubular epithelial cells membrane
		Glucose transporter 9(GLUT9)	Located in both apical and basolateral side of the proximal tubular epithelial cells membrane