Table 2. Summarized data of clinical and pathological parameters from the eligible studies.
| First author | Gender | Tumor differentiation | Tumor size | Lymph node metastasis | Distant metastasis | Clinical stage | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | Poor+Moderate/ undifferentiated |
Well/differentiated | T3–4 | T1–2 | Yes | No | Yes | No | III-IV | I-II | ||||||||||||||
| TrkB+ | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | + | - | ||
| Tanaka K [16] | 50 | 181 | 17 | 72 | 24 | 143 | 43 | 110 | 47 | 129 | 20 | 124 | 43 | 119 | 24 | 134 | 6 | 11 | 61 | 242 | 37 | 94 | 30 | 159 | |
| Fan M [19] | 49 | 52 | 56 | 34 | 66 | 57 | 39 | 29 | NA | NA | NA | NA | 52 | 21 | 53 | 65 | 18 | 6 | 87 | 80 | 40 | 32 | 65 | 54 | |
| Li SS [21] | 31 | 56 | 12 | 9 | 39 | 61 | 4 | 4 | 24 | 21 | 19 | 44 | 38 | 43 | 5 | 22 | 7 | 5 | 36 | 60 | 42 | 52 | 1 | 13 | |
| Okugawa Y [17] | 54 | 65 | 10 | 21 | 25 | 50 | 39 | 36 | 46 | 52 | 18 | 34 | 50 | 55 | 14 | 31 | 6 | 6 | 58 | 80 | 47 | 55 | 17 | 31 | |
| Okamura K [22] | 54 | 18 | 23 | 7 | 56 | 15 | 13 | 9 | 9 | 4 | 68 | 21 | 26 | 6 | 51 | 19 | NA | NA | NA | NA | 16 | 4 | 61 | 21 | |
| Sasahira T [24] | 21 | 47 | 11 | 23 | 11 | 27 | 21 | 43 | 19 | 32 | 13 | 38 | 17 | 30 | 15 | 40 | NA | NA | NA | NA | 23 | 42 | 9 | 28 | |
| Zhang Y [18] | 43 | 67 | 21 | 30 | 20 | 51 | 44 | 46 | 27 | 22 | 37 | 75 | 27 | 34 | 37 | 63 | 14 | 3 | 50 | 94 | NA | NA | NA | NA | |
| Dawson H [20] | 27 | 41 | 26 | 46 | 48 | 74 | 4 | 13 | 44 | 71 | 8 | 16 | 31 | 48 | 21 | 39 | 11 | 8 | 42 | 78 | NA | NA | NA | NA | |
| Li L [26] | 13 | 7 | 5 | 2 | 15 | 3 | 3 | 6 | 14 | 4 | 4 | 5 | 6 | 1 | 12 | 8 | NA | NA | NA | NA | 16 | 4 | 2 | 5 | |