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. 2017 Jul 26;8(59):99414–99428. doi: 10.18632/oncotarget.19562

Table 2. β-catenin expression and clinicopathological variables of astrocytoma.

Pathological features Cases β-catenin score, n (%) rs P valuea
0-99 100-199 200-300
Ageb 160 0.542
Tumor sizec 160 0.503
Gender 0.100 0.209
 Male 95 31 (32.6) 42 (44.2) 22 (23.2)
 Female 65 18 (27.7) 25 (38.5) 22 (33.8)
Histological grade 0.287 0.000
 Grade II 47 23 (48.9) 19 (40.4) 5 (10.6)
 Grade III 48 11 (22.9) 24 (50.0) 13 (27.1)
 Grade IV 65 15 (23.1) 24 (36.9) 26 (40.0)
Peritumoral edema 0.032 0.689
 Weak 35 9 (25.7) 15 (42.9) 11 (31.4)
 Moderate 78 28 (35.9) 33 (42.3) 17 (21.8)
 Strong 47 12 (25.5) 19 (40.4) 16 (34.0)
Location 0.096 0.192
 Frontal 54 18 (33.3) 23 (42.6) 13 (24.1)
 Temporal 47 13 (27.6) 17 (36.2) 17 (36.2)
 Parietal 14 6 (42.8) 4 (28.6) 4 (28.6)
 Occipital 7 3 (42.9) 4 (57.1) 0 (0.0)
 Cerebrum 4 1 (25.0) 3 (75.0) 0 (0.0)
 Callosum/ventricle/thalamus 12 5 (41.7) 3 (25.0) 4 (33.3)
 More than one lobe 22 3 (13.6) 13 (59.1) 6 (27.3)

aP values were calculated by Spearman’s Rank-Correlation test.

bAge: 49 (9–80) years, F = 0.619, P = 0.542 (ANOVA test).

cTumor size: (4.7 ± 1.6) cm, F = 0.690, P = 0.503 (ANOVA test).