Table 4. Univariate and multivariate analysis for overall survival (OS) analysis.
| Variables | Univariate | Multivariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
| Age | 1.031 | 1.017–1.045 | 0.000 | 1.025 | 1.010–1.040 | 0.001 | 1.026 | 1.011–1.041 | 0.001 |
| Gender (male/female) | 0.949 | 0.620–1.455 | 0.812 | ||||||
| Tumor size (≤ 5 cm versus > 5 cm) | 1.795 | 1.169–2.758 | 0.008 | 1.812 | 1.162–2.825 | 0.009 | 1.889 | 1.205–2.961 | 0.006 |
| Histological grade (II versus III versus IV) | 1.966 | 1.486–2.599 | 0.000 | 1.716 | 1.272–2.316 | 0.000 | 1.761 | 1.315–2.357 | 0.000 |
| Peritumoral edema | 1.249 | 0.951–1.641 | 0.110 | ||||||
| Surgical excision (complete versus partial) | 0.697 | 0.399–1.216 | 0.204 | ||||||
| Radiotherapy (yes/no) (post operation) | 0.725 | 0.476–1.105 | 0.135 | ||||||
| Chemotherapy (yes/no) (post operation) | 0.679 | 0.433–1.065 | 0.092 | ||||||
| AQP1 expression (high/low) | 1.954 | 1.185–3.222 | 0.009 | 1.449 | 0.858–2.448 | 0.166 | |||
| β-catenin expression (high/low) | 1.805 | 1.059–3.075 | 0.030 | 1.523 | 0.879–2.637 | 0.133 | |||