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. 2017 Sep 16;8(59):99801–99815. doi: 10.18632/oncotarget.21068

Figure 6. Macrophages induced SOX9-dependent EMT-like phenotype in lung cancer cells.

Figure 6

SOX9 expression was inhibited in A549 and H1299 cells via RNAi. (A) Changes in lung cancer cell morphology after macrophage supernatant was added to A549 and H1299 cells or after co-culture of macrophages with A549 and H1299 cells for 48h. (B) Changes in SOX9, E-cadherin, and vimentin protein levels in lung cancer cells after macrophage supernatant was added to A549 and H1299 cells or after co-culture of macrophages with A549 and H1299 cells for 48h.