Figure 8. Macrophages promote SOX9-dependent invasion in lung cancer cells.

SOX9 expression was inhibited in A549 cells via RNAi. (A) Invasion assays were performed 48 hours after macrophage supernatant was added to A549 cells or after co-culture of macrophages with A549 cells. (B) Total numbers of invaded cells were quantified after macrophage supernatant was added to A549 cells or after co-culture of macrophages with A549 cells. ^***p < 0.01, mean ± SEM.