Table 2.
The mean Aβ, measured by the florbetapir AV45 standardized uptake value ratio, was compared between participants with and without T2DM in different brain regions
| Brain region | T2DM (n = 74) | Nondiabetics (n = 724) | P value |
|---|---|---|---|
| Anterior cingulate | 1.64 ± 0.05 (95% CI: 1.54–1.74) | 1.75 ± 0.02 (95% CI: 1.70–1.80) | .043 |
| Frontal lobe | 1.47 ± 0.04 (95% CI: 1.39–1.54) | 1.55 ± 0.02 (95% CI: 1.51–1.59) | .054 |
| Limbic lobe | 1.57 ± 0.04 (95% CI: 1.50–1.65) | 1.64 ± 0.02 (95%CI: 1.61–1.68) | .104 |
| Occipital lobe | 1.35 ± 0.03 (95% CI: 1.28–1.41) | 1.42 ± 0.02 (95% CI: 1.39–1.45) | .057 |
| Parietal lobe | 1.43 ± 0.04 (95% CI: 1.34–1.51) | 1.52 ± 0.02 (95% CI: 1.48–1.56) | .062 |
| Posterior cingulate | 1.50 ± 0.05 (95% CI: 1.41–1.59) | 1.59 ± 0.02 (95% CI: 1.55–1.63) | .085 |
| Precuneus | 1.42 ± 0.05 (95% CI: 1.33–1.52) | 1.54 ± 0.02 (95% CI: 1.50–1.59) | .021 |
| Temporal lobe | 1.43 ± 0.04 (95% CI: 1.35–1.51) | 1.52 ± 0.02 (95% CI: 1.48–1.56) | .04 |
Abbreviations: Aβ, amyloid β; T2DM, type 2 diabetes mellitus.