Figure 1.

Species Tree for PTEN-L and Alignment of PTEN-L Sequences

(A) Species tree for PTEN-L. The species tree was generated as described in the Results. UL_max(nt) and UI_max(aa) indicate numbers of conserved nucleotides and amino acids, respectively. The column labeled CTG-IF indicates whether the CTG initiation codon for endogenous PTEN-L is present. The column labeled Palindrome indicates whether the palindromic sequence identified by Liang et al.²² as being required for initiation of PTEN-L expression is present. (B) Alignment of PTEN-L sequences. Alignments were generated as described in the Results. The black bar indicates the proposed leader sequence in PTEN-L.