Table 1.

Up-regulated, differentially-expressed genes in the kidney of Aldh16a1 KO mice. Gene transcription profiling was obtained by RNA-sequencing of renal RNA from wild-type (WT) and Aldh16a1 knockout (KO) mice. Genes with fold change > log₂ 1and false discovery rate (FDR) controlled p-value ≤ 0.05 in KO samples relative to WT samples were arbitrarily defined as being differentially-expressed. The transcripts in KO mice that differed most from WT mice is ranked in fold-change, with the ten genes that were most up-regulated being listed.

Gene symbol	Gene ID (Mus musculus)	Log2 FC	q-valuea
Cyp2j13	230459	8.83	2.78 × 10−3
Slc7a13	74087	8.20	2.78 × 10−3
Acsm3	20216	7.45	2.78 × 10−3
Gm12839	631037	5.21	2.78 × 10−3
Pzp	11287	4.80	2.78 × 10−3
Ugt2b5	22238	4.65	2.78 × 10−3
Col6a6	245026	4.56	2.78 × 10−3
Tbx10	109575	4.36	8.96 × 10−3
Slc22a30	319800	4.11	2.78 × 10−3
Timd2	171284	4.10	2.78 × 10−3

^aFDR controlled p-value.