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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2017 Sep 13;27(1):210–220. doi: 10.1016/j.jstrokecerebrovasdis.2017.08.028

Table 3.

Multivariable models of outcomes

Competing risk models with death as competing risk Cox regression
Outcome Any event Stroke MI Stroke or MI Death
Variable HR (95% CI) p-value HR (95% CI) p-value HR (95% CI) p-value HR (95% CI) p-value HR (95% CI) p-value
Whole sample**
Age 1.01 (1.00–1.01) <0.0001 0.99 (0.99–0.99) <0.0001 0.99 (0.98–0.99) <0.0001 0.99 (0.99–0.99) <0.0001 1.06 (1.06–1.06) <0.0001
Female sex 0.96 (0.93– 0.99) 0.004 1.05 (0.98–1.12) 0.2 0.88 (0.81–0.95) 0.001 0.98 (0.93–1.03) 0.4 0.95 (0.92–0.99) 0.01
Among those ≥65 yr without adjustment for medications**
Age 1.00 (0.99–1.00) 0.02 0.98 (0.98–0.99) <0.0001 0.97 (0.96–0.98) <0.0001 0.98 (0.98–0.98) <0.0001 1.07 (1.06–1.07) <0.0001
Female sex 0.94 (0.91–0.97) 0.0006 1.06 (0.98–1.14) 0.1 0.93 (0.84–1.02) 0.1 1.01 (0.95–1.07) 0.7 0.93 (0.90–0.97) 0.0005
Among those ≥65 yr with adjustment for medications@
Age 1.00 (1.00–1.00) 0.6 0.99 (0.98–0.99) <0.0001 0.98 (0.97–0.98) <0.0001 0.98 (0.98–0.99) <0.0001 1.06 (1.06–1.06) 0.0001
Female sex 0.94 (0.91–0.97) 0.0004 1.06 (0.98–1.14) 0.1 0.92 (0.84–1.02) 0.1 1.01 (0.95–1.07) 0.8 0.93 (0.89–0.97) 0.0002

MI=myocardial infarction; HTN=hypertension; CAD=coronary artery disease; PVD=peripheral vascular disease;

male sex as referent;

**

models are adjusted for: income, hypertension, atrial fibrillation, stroke or TIA, MI, CAD, PVD, and Charlson score;

@

models are adjusted for: income, hypertension, atrial fibrillation, stroke or TIA, MI, CAD, PVD, Charlson score, anti-hypertensive medication use, diabetes medication use, statin use, and warfarin use

HHS Vulnerability Disclosure