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. 2017 Dec 7;23(45):8053–8061. doi: 10.3748/wjg.v23.i45.8053

Table 5.

HADS and WHOQOL-BREF scores in the control and functional dyspepsia groups according to gender

Variables Control
FD
P value1
Total Male Female Total Male Female Control vs FD Control2 FD2
(n = 87) (n = 38) (n = 49) (n = 104) (n = 39) (n = 65)
HADS score3 (mean ± SE)
Total 11.0 ± 0.8 10.8 ± 1.2 11.2 ± 1.1 15.8 ± 1.2 13.2 ± 1.3 18.6 ± 2.1 0.001 0.780 0.029
Anxiety 5.1 ± 0.4 4.9 ± 0.6 5.3 ± 0.6 7.4 ± 0.7 6.0 ± 0.7 9.0 ± 1.3 0.005 0.587 0.036
Depression 5.9 ± 0.4 5.9 ± 0.7 5.9 ± 0.6 8.4 ± 0.6 7.2 ± 0.8 9.7 ± 1.0 0.001 0.984 0.047
WHOQOL-BREF score4 (mean ± SE)
Total 59.5 ± 1.6 60.7 ± 2.7 58.0 ± 1.5 54.0 ± 1.9 57.5 ± 1.9 51.6 ± 2.1 0.027 0.417 0.074
Overall quality of life and general health 6.2 ± 0.2 6.6 ± 0.3 5.8 ± 0.3 5.9 ± 0.3 6.5 ± 0.3 5.4 ± 0.3 0.278 0.080 0.020
Physical domain 13.4 ± 0.4 13.6 ± 0.7 13.1 ± 0.4 12.6 ± 0.4 13.6 ± 0.5 11.6 ± 0.7 0.185 0.575 0.016
Psychological domain 12.8 ± 0.4 13.2 ± 0.7 12.4 ± 0.5 11.8 ± 0.4 12.4 ± 0.5 11.4 ± 0.7 0.092 0.410 0.278
Social domain 13.7 ± 0.4 14.0 ± 0.6 13.3 ± 0.4 12.1 ± 0.5 13.0 ± 0.5 11.5 ± 0.6 0.012 0.370 0.064
Environment domain 13.3 ± 0.5 13.3 ± 0.7 13.3 ± 0.6 11.6 ± 0.4 12.1 ± 0.5 11.7 ± 0.7 0.010 0.990 0.617
1

t-test was used;

2

Between males and females;

3

Higher score denotes more severe symptom;

4

Higher score denotes better quality of life. FD: Functional dyspepsia; HADS: Hospital anxiety and depression scale; WHOQOL-BREF: World health organization quality of life abbreviated version.