Table 1.

Studies included in systematic review

Study ID	Yr	Study period	Type of study	Sample size	IBD patients with active disease	IBD patients with inactive disease	Outcomes
Disease activity and SGA
Bröms et al[19]	2014	2006-2010	R	470110	988	972	SGA and LBW
Bush et al[20]	2004	1986-2001	R	56514	22	94	SGA and LBW
de Lima-Karagiannis et al[21]	2016	2008-2014	P	298	92	134	SGA and LBW
Moser et al[6]	2000	1993-1997	R	130	13	52	SGA
Stephansson et al[27]	2011	1994-2006	R	871579	No raw data provided		SGA
Mahadevan et al[26]	2012		P	797	No raw data provided		SGA
Disease activity and LBW
Bortlik et al[24]	2013	2007-2012	R	41	10	31	LBW
Bröms et al[19]	2014	2006-2010	R	470110	988	972	SGA and LBW
Bush et al[20]	2004	1986-2001	R	56514	22	94	SGA and LBW
de Lima-Karagiannis et al[21]	2016	2008-2014	P	298	92	134	SGA and LBW
Molnár et al[28]	2010		R	167	No raw data provided		LBW
Bortoli et al[7]	2011	2003-2006	P	664	No raw data provided		LBW
Treatment and SGA					Thiopurine exposure	Non thiopurine exposure
Bröms et al[19]	2014	2006-2010	R	470110	421	1539	SGA and LBW
Cleary BJ(23)	2009	1995-2007	R	1164030	315	676	SGA and LBW
Treatment and LBW
Bröms et al[19] (AZA)	2014	2006-2010	R	470110	421	1539	SGA and LBW
Cleary et al[23]	2009	1995-2007	R	1164030	315	1676	SGA and LBW
Komoto et al[25] (AZA)	2016	2008-2014	R	72	7	29	LBW
Nørgård et al[5]	2007	1996-2004	R	900	20	628	LBW
Shim et al[22]	2011	1996-2006	R	93	19	74	LBW
Nørgård et al[10]	2003	1991-2000	R	19437	No raw data provided		LBW

R: Retrospective study; P: Prospective study; IBD: Inflammatory bowel disease; SGA: Small for gestational age; LBW: Low birth weight.