Table 1. Clinical and biochemical characteristics of 58 obese children.
| Characteristic | Value |
|---|---|
| Male sex | 38 (65.5) |
| Age (yr) | 11.6±2.9 |
| Weight (kg) | 72.9±23.1 |
| Height (cm) | 149.9±15.0 |
| BMI z score | 5.1±2.2 |
| Waist circumference (cm) | 97.5±14.6 |
| Prepubertal stage | |
| Female:male | 3 (5.1):17 (29.3) |
| Family history of diabetes mellitus | 25 (43.1) |
| Family history of hypertension | 28 (48.3) |
| Family history of dyslipidemia | 16 (27.6) |
| Glucose homeostasis | |
| Fasting blood glucose (mg/dL) | 85.0±7.9 |
| Impaired fasting glucose | 1 (1.7) |
| Diabetes | 0 (0) |
| 2-Hour glucose during OGTT (mg/dL) | 117.0±18.6 |
| Impaired glucose tolerance | 9 (15.5) |
| Diabetes | 0 (0) |
| Insulin | |
| Fasting insulin (µU/mL) | 21.8±13.3 |
| >15 µU/mL | 36 (62.1) |
| 2-Hour insulin during OGTT (µU/mL) | 150.7±113.4 |
| >75 µU/mL | 44 (75.9) |
| Index for insulin resistance | |
| HOMA-IR | 4.6±2.8 |
| >3.16 | 35 (60.3) |
| Lipid profiles | |
| Triglyceride (mg/dL) | 117.2±65.4 |
| Hypertriglyceridemia | 14 (24.1) |
| HDL-cholesterol (mg/dL) | 41.4±8.1 |
| Low HDL | 26 (44.8) |
| Cholesterol (mg/dL) | 183.0±42.4 |
| Hypercholesterolemia | 17 (29.3) |
| LDL-cholesterol (mg/dL) | 121.4±39.5 |
| High LDL-cholesterol | 18 (31.0) |
| Inflammatory markers | |
| hs-CRP (mg/L) | 6.37±6.68 |
| >3 mg/L | 40 (69.0) |
| IL-6 (pg/mL) | 39.1±77.5 |
| TNF-α (pg/mL) (n=53) | 12.1±38.6 |
Values are presented as number (%) or mean±standard deviation.
BMI, body mass index; OGTT, oral glucose tolerance test; HOMA-IR, homeostasis model assessment of insulin resistance; HDL, high-density lipoprotein; LDL, low-density lipoprotein; hs-CRP, high sensitivity C-reactive protein; IL-6, interleukin-6; TNF-α, tumor necrosis factor-alpha.