Table 4. Odds Ratios for Elevated HbA1c (≥5.9%) in People without Diabetes and High HbA1c (≥7.9%) in People with Diabetes according to FHD Using Logistic Regression Analysis.
| Classification of FHD | Non-diabetes (n=7031) | Diabetes (n=1918) | ||
|---|---|---|---|---|
| n (%) | HbA1c≥5.9%* | n (%) | HbA1c≥7.9%† | |
| Negative (none) | 6046 (86.0) | 1.00 | 1366 (71.2) | 1.00 |
| Father only | 103 (1.5) | 1.22 (0.72–2.06) | 37 (1.9) | 0.78 (0.32–1.88) |
| Mother only | 183 (2.6) | 1.34 (0.91–1.98) | 88 (4.6) | 2.23 (1.35–3.70) |
| Siblings only | 617 (8.8) | 1.35 (1.10–1.66) | 342 (17.8) | 1.22 (0.90–1.65) |
| Father and mother | 9 (0.1) | 0.81 (0.10–6.64) | 9 (0.5) | 1.28 (0.27–6.00) |
| Father and siblings | 19 (0.3) | 1.84 (0.64–5.29) | 21 (1.1) | 1.02 (0.36–2.89) |
| Mother and siblings | 50 (0.7) | 1.44 (0.70–2.93) | 45 (2.3) | 1.45 (0.73–2.88) |
| Father, mother, and siblings | 4 (0.1) | - | 10 (0.5) | 1.45 (0.33–6.42) |
HbA1c, hemoglobin A1c; FHD, family history of diabetes; SBP, systolic blood pressure; HDL, high-density lipoprotein.
Data are presented as odds ratio (95% confidence interval).
*Adjusted for age, gender, education, body mass index, waist circumference, smoking status, alcohol consumption, medication to treat hypertension, medication to treat dyslipidemia, SBP, total cholesterol, HDL cholesterol, and triglycerides, †Adjusted for age, gender, education, body mass index, waist circumference, smoking status, alcohol consumption, medication to treat hypertension, medication to treat dyslipidemia, SBP, total cholesterol, HDL cholesterol, triglycerides, diabetes duration, and medication to treat diabetes.