Table 1.
Characteristics of MS patients and controls.
| NBB | Autopsy | Sex | Age | Diagnosis | Specific |
|---|---|---|---|---|---|
| 1997-160 | S97/385 | f | 40 | Multiple sclerosis | #5 2,2,2,4,4 |
| 1997-160 | S97/385 | f | 40 | Multiple sclerosis | #6 2,3 |
| 2004-007 | S04/029 | f | 50 | Multiple sclerosis | #2 chron.act. |
| 2004-007 | S04/029 | f | 50 | Multiple sclerosis | #5 chron.inact. |
| 2009-103 | S09/317 | f | 59 | Multiple sclerosis | #1 3(3),4,6 |
| 2006-027 | S06/082 | f | 77 | Multiple sclerosis | #1 4,6 |
| 2006-054 | S06/178 | m | 66 | Multiple sclerosis | #3 active |
| 2006-054 | S06/178 | m | 66 | Multiple sclerosis | #5 chron.inact. |
| 2009-034 | S09/104 | m | 45 | Multiple sclerosis | #5 3(2),4,6 |
| 2012-084 | S12/084 | m | 63 | Multiple sclerosis | #1 1,3(1),4,5I,5II,5II |
| 2007-057 | S07/216 | m | 71 | Multiple sclerosis | #2 4,6,6 |
| 1994-119 | S94/325 | f | 51 | Non-demented control | |
| 1994-123 | S94/338 | f | 76 | Non-demented control | |
| 2012-071 | S12/071 | f | 57 | Non-demented control | |
| 1996-032 | 96/052. | f | 60 | Non-demented control | |
| 1995-092 | S95/258 | f | 63 | Non-demented control | |
| 2012-049 | S12/049 | f | 70 | Non-demented control | |
| 1995-011 | *95/026 | m | 62 | Non-demented control | |
| 1995-084 | S95/240 | m | 72 | Non-demented control | |
| 2011-069 | S11/069 | m | 49 | Non-demented control | |
| 2000-090 | S00/185 | m | 70 | Non-demented control | |
| 1995-084 | S95/240 | m | 72 | Non-demented control |
Annotation for staging and characterization of MS lesions from NBB: #1: Reactive (groups of HLA-positive microglial cells, no demyelination); #2: Active lesion (demyelination, HLA positive microglial cells throughout the lesion); #3: Chronic active lesion (hypocelular gliotic centre, active border with HLA-positive macrophages/microglial cells); Sub score 1–3 reflects degree of activation of HLA positive microglial cells: ramified appearance = 1 up to big rounded foamy morphology = 3; #4: Gliotic inactive hypocellular lesion, with some HLA-positive microgliosis; #5: Grey matter lesion (for cortex not for spinal cord); 6 Shadow plaque.