Table 1.

KEGG pathway analysis of neuronal DEGs.

ID	Term	KEGG ID	Overlap	P-value	Adjusted P-value	Z-score	Combined Score	Genes
1	Complement and coagulation cascades	hsa04610	5/79	0.0002	0.0274	−1.824	6.559	Fga, Procr, F9, C6, C2
2	Phototransduction	hsa04744	2/27	0.0157	0.6136	−1.96	0.957	Rcvrn, Rho
3	Neuroactive ligand-receptor interaction	hsa04080	5/277	0.0384	0.6136	−1.821	0.89	Gabrr3, P2ry10, Chrnb4, Chrm5, Tacr2
4	Beta-alanine metabolism	hsa00410	2/31	0.0201	0.6136	−1.785	0.872	Aoc3, Srm
5	Melanoma	hsa05218	2/71	0.0847	0.6136	−1.686	0.823	E2f2, Fgf22
6	Carbohydrate digestion and absorption	hsa04973	2/45	0.0388	0.6136	−1.674	0.818	Atp1a4, Lct
7	Cytokine-cytokine receptor interaction	hsa04060	4/265	0.1029	0.6136	−1.588	0.776	Il7, Ccl3, Gdf5, Il6r
8	Adherens junction	hsa04520	2/74	0.0907	0.6136	−1.568	0.766	Tcf7l2, Map3k7
9	Bile secretion	hsa04976	2/71	0.0847	0.6136	−1.531	0.748	Atp1a4, Baat
10	Arrhythmogenic right ventricular cardiomyopathy	hsa05412	2/74	0.0907	0.6136	−1.475	0.721	Tcf7l2, Sgca
11	Cardiac muscle contraction	hsa04260	2/78	0.099	0.6136	−1.443	0.705	Atp1a4, Tnni3
12	Prostate cancer	hsa05215	2/89	0.1226	0.6136	−1.438	0.703	Tcf7l2, E2f2
13	Hypertrophic cardiomyopathy	hsa05410	2/83	0.1095	0.6136	−1.425	0.696	SgcA, Tnni3
14	Dilated cardiomyopathy	hsa05414	2/90	0.1248	0.6136	−1.322	0.646	Sgca, Tnni3
15	Cholinergic synapse	hsa04725	2/111	0.1732	0.6136	−1.29	0.63	Chrnb4, Chrm5
16	Hematopoietic cell lineage	hsa04640	2/88	0.1204	0.6136	−1.29	0.63	Il7, Il6r
17	Salmonella infection	hsa05132	2/86	0.116	0.6136	−1.249	0.61	Klc3, Ccl3
18	Regulation of actin cytoskeleton	hsa04810	3/214	0.1749	0.6136	−1.228	0.6	Chrm5, Myl10, Fgf22
19	HIF-1 signaling pathway	hsa04066	2/103	0.1544	0.6136	−1.198	0.585	Cybb, Il6r
20	Toll-like receptor signaling pathway	hsa04620	2/106	0.1614	0.6136	−1.196	0.584	Ccl3, Map3k7