Table 2.

KEGG pathway analysis of astrocytic DEGs.

ID	Term	KEGG ID	Overlap	P-value	Adjusted P-value	Z-score	Combined Score	Genes
1	Cytokine-cytokine receptor interaction	hsa04060	5/265	0.0045	0.1614	−1.877	3.424	Ccr1, Il2rb, Ccl4, Ccl3, Cxcl2
2	Chemokine signaling pathway	hsa04062	4/187	0.0073	0.1614	−1.876	3.423	Ccr1, Ccl4, Ccl3, Cxcl2
3	Salmonella infection	hsa05132	3/86	0.0056	0.1614	−1.695	3.092	Ccl4, Ccl3, Cxcl2
4	Vascular smooth muscle contraction	hsa04270	3/120	0.0137	0.2254	−1.789	2.666	Ptgir, Pla2g2c, Ramp1
5	Neuroactive ligand-receptor interaction	hsa04080	4/277	0.0269	0.355	−1.797	1.861	Uts2r, Ptgir, Npy2r, Gnrhr
6	Toll-like receptor signaling pathway	hsa04620	2/106	0.0724	0.4737	−1.685	1.259	Ccl4, Ccl3
7	NF-kappa B signaling pathway	hsa04064	2/93	0.0578	0.4737	−1.625	1.214	Ccl4, Cxcl2
8	Oxytocin signaling pathway	hsa04921	2/158	0.1401	0.4737	−1.579	1.18	Cacng1, Kcnj3
9	Transcriptional misregulation in cancer	hsa05202	2/180	0.1719	0.4737	−1.302	0.973	Wt1, Il2rb
10	Ras signaling pathway	hsa04014	2/227	0.243	0.4737	−1.258	0.94	Pla2g2c, Rasgrp4
11	MAPK signaling pathway	hsa04010	2/255	0.2862	0.4737	−1.132	0.846	Cacng1, Rasgrp4
12	Tryptophan metabolism	hsa00380	1/40	0.1561	0.4737	−1.088	0.813	Inmt
13	Regulation of lipolysis in adipocytes	hsa04923	1/56	0.2104	0.4737	−1.086	0.812	Fabp4
14	Prion diseases	hsa05020	1/35	0.1384	0.4737	−1.043	0.779	C6
15	Legionellosis	hsa05134	1/55	0.2071	0.4737	−1.036	0.774	Cxcl2
16	Selenocompound metabolism	hsa00450	1/17	0.0717	0.4737	−1.029	0.769	Inmt
17	Vitamin digestion and absorption	hsa04977	1/24	0.0982	0.4737	−1.016	0.759	Slc52a3
18	Long-term depression	hsa04730	1/60	0.2235	0.4737	−0.994	0.743	Ppp1r17
19	Fat digestion and absorption	hsa04975	1/41	0.1596	0.4737	−0.934	0.698	Pla2g2c
20	Arachidonic acid metabolism	hsa00590	1/62	0.2299	0.4737	−0.912	0.682	Pla2g2c