Table 1.
CLOCK rs1801260 | PER2 rs2304672 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Case n = 646 |
Control n = 352 |
OR | 95% CI | P value | Case n = 646 |
Control n = 352 |
OR | 95% CI | P value | ||
Genotype | Genotype | ||||||||||
TT | 522 (80.8) | 313 (88.8) | Reference | CC | 573 (88.7) | 325 (92.3) | Reference | ||||
TC | 108 (16.7) | 35 (9.9) | 1.818 | 1.212–2.728 | 0.004a | CG | 69 (10.7) | 26 (7.4) | 1.499 | 0.936–2.401 | 0.090 |
CC | 16 (2.5) | 4 (1.1) | 2.058 | 0.733–6.661 | 0.149 | GG | 4 (0.6) | 1 (0.3) | 2.187 | 0.243–4.642 | 0.474 |
Dominant effect | Dominant effect | ||||||||||
CC+TC vs TT | 124/522 | 39/313 | 1.906 | 1.296–2.805 | 0.001a | GG+CG vs CC | 73/573 | 27/325 | 1.534 | 0.966–2.434 | 0.068 |
Allele | Allele | ||||||||||
T | 1152 (89.2) | 661 (93.9) | Reference | C | 1215 (94.0) | 676 (96.0) | Reference | ||||
C | 140 (10.8) | 43 (6.1) | 1.868 | 1.310–2.644 | 0.001a | G | 77 (6.0) | 28 (4.0) | 1.530 | 0.983–2.382 | 0.058 |
The Chi-square test was used to compare categorical variables.
a P < 0.01.