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. 2017 Dec 11;7:119. doi: 10.1186/s13613-017-0341-y

Table 4.

Thrombotic events in ICU

No. of thrombotic events—no (%) 11 (9)
Site of thrombosis
 Brain 5
 Arm, fingers, toes 2
 Liver veins 2
 Spleen (post-mortem finding) 1
 Inferior vena cava 1
Haematological diagnosis
 AML 10
 ALL 1
 MDS 0
Severe sepsis/septic shock—no (%) 11 (100)
Death directly related to thrombosis—no 4
Bleeding prior to thrombotic event 3
Bleeding after thrombotic event 3
LMWHa 4
Drugs given prior to thrombotic event
 Tranexamic acid 2 b
 Vitamin K 2 c

Data are in number (%)

AML acute myeloid leukaemia, ALL acute lymphoblastic leukaemia, MDS myelodysplastic syndrome, LMWH low molecular weight heparin

aEnoxaparin 20–40 mg daily in ICU before thrombotic event

bSite of thrombi: 1. spleen (post-mortem finding); 2. thalamus (MRI finding)

cSite of thrombi: 1. inferior vena cava; 2. brain (multiple sites)