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. 2017 Dec 7;8:1015. doi: 10.3389/fphys.2017.01015

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Copyright © 2017 Moo, Leonard and Herzog.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in local dispersion of sarcomere lengths (SLs) due to activation are shown using (A) the local standard deviation (SD) and, (B) the local coefficient of variation (CV), and were measured at the short and long muscle lengths. Muscle activation resulted in increased dispersion in SLs. The increase in dispersion was more pronounced for sarcomeres at the short compared to the long muscle length. ^*Indicates significant differences in local SD or in local CV compared with sarcomeres in the relaxed muscle at either the short or the long length (p < 0.01). ^†Indicates significant differences in local SD or in local CV compared with sarcomeres in either the relaxed or the activated muscle at the short length (p < 0.01).