Fig. 7.

Electrical synaptic inputs are necessary for OS. a Polar plot of drifting grating responses of an example OFF OS RGC. b, c Polar plot of drifting grating responses of the same cell in a in current clamp before (b) and after (c) bath application of MFA. d, e Raw traces of recorded membrane potentials of the same cell in a along preferred and null orientations before (d) and after (e) bath application of MFA. f Polar plot of drifting grating responses of an example OFF OS RGC. g Polar plot of drifting grating responses of the same cell in f in current clamp after intracellular application of quinine. h Raw traces of recorded membrane potentials of the same cell in f along preferred and null orientations after intracellular application of quinine. i OSI of drifting gratings responses in cell attached mode (grey) and in current clamp mode before (grey) and after (purple) MFA application. Error bars indicate SEM across n = 4 (n = 2 OFF hOS and n = 2 OFF vOS) cells. Dashed lines connect measurements from the same cell. j OSI of drifting gratings responses in cell attached mode (grey) and in current clamp mode after quinine application (pink). Error bars indicate SEM across n = 4 (n = 2 OFF hOS and n = 2 OFF vOS) cells. *p  < 0.05